Using a combination of biochemical, biophysical, and computer modelling tools, the team discovered that lapatinib causes HER2 receptors on cell membranes to pair up with a partner receptor called HER3. When you combine these inhibitor-induced HER2-HER3 pairs with naturally-occurring growth signals from outside of the cell, they can rearrange themselves into an active, signalling pair. In this state, the HER2-HER3 pair becomes very efficient at telling the cells to divide, more so than cells that haven't been treated with the drug.Essentially, lapatinib causes the cancer-causing protein HER2 to have an even stronger influence on cancer cell growth than it would normally possess. The researchers say that their findings will hopefully guide future research and the development of a "better" drug. However, taking this drug seems to be worse than not treating your cancer at all -- so what qualifies as "better" may be debatable.
In a study by the Beth Israel Deaconess Medical Center, radiation and chemotherapy treatments that kill tumor cells were found to cause cancerous tumors to grow bigger and more prolific. In fact, the dying cancer cells that chemotherapy set into motion actually trigger the inflammation that causes tumors to grow more aggressively.It seems that hardly any of modern medicine's "treatments" actually work when it comes to halting cancer (see Cancer.news for more coverage). Nonetheless, you can learn more about natural remedies and other health solutions at AlternativeMedicine.news. Sources for this article include: ScienceDaily.com ElifeSciences.org
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