New study shows collagen and vitamin C improve skin aging and scalp health
By willowt // 2025-08-28
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  • Collagen and vitamin C supplementation significantly reduced skin collagen fragmentation by 44.6% and increased skin hydration by 13.8%.
  • The supplement improved scalp health by 11% and increased hair density by 27.6%.
  • Research supports collagen's role in improving nail growth and reducing brittleness.
  • The study reveals the combined benefits of collagen and vitamin C on skin, scalp and hair, with daily use showing the best results.
  • Clinical trials and systematic reviews provide strong evidence for the effectiveness of collagen and vitamin C supplements.
A groundbreaking clinical study published in Dermatology Research and Practice has shed light on the significant benefits of combining collagen and vitamin C supplements. Conducted over 12 weeks, the study involved 140 men and women aged 40 to 60, aiming to determine the impact of a daily collagen and vitamin C supplement on skin aging, scalp health and hair growth. The results are compelling, offering clear evidence that this combination can significantly enhance skin hydration, reduce wrinkles, and improve hair density and quality.

The science behind the study

Collagen is the most abundant protein in the skin, providing structural support and maintaining its elasticity and hydration. Vitamin C, on the other hand, is a key cofactor in collagen synthesis, playing a crucial role in the formation and stability of collagen fibers. Together, these two nutrients form a powerful duo that can combat the visible signs of aging and enhance overall skin and hair health. Methodology:
  • Participants: 140 men and women aged 40 to 60.
  • Supplement: 8 grams of hydrolyzed collagen peptides and 60 milligrams of vitamin C.
  • Placebo: Matched in taste, texture, color and viscosity.
  • Assessments: Advanced tools including confocal microscopy, ultrasound and visual grading scales were used to measure changes in skin collagen, hydration, elasticity and scalp health.

Key findings: Transformative benefits for skin and hair

After 12 weeks of daily supplementation, the participants experienced several significant improvements:
  1. Improved Skin Health
    • Collagen fragmentation: A 44.6% decrease in skin collagen fragmentation, indicating a reduction in the breakdown of collagen fibers.
    • Hydration: Skin hydration increased by 13.8%, crucial for maintaining skin health and appearance.
    • Elasticity: The R2 elasticity index increased by 22.7%, suggesting improved skin firmness and reduced sagging.
    • Wrinkles: Wrinkle depth decreased by 19.6%, a notable reduction in visible signs of aging.
  2. Enhanced hair quality
    • Scalp health: Scalp scaling improved by 11%, indicating healthier scalp conditions.
    • Hair density: The total number of hairs per unit area increased by 27.6%, suggesting more robust hair growth.
    • Hair appearance: Expert visual grading showed a 31.9% improvement in hair health, with participants reporting thicker, more voluminous and shinier hair.

The broader implications: Beyond skin and hair

While the study primarily focused on skin and hair, the implications extend to other areas of health. Collagen and vitamin C are also known to support:
  • Digestive health: Research from the journal Marine Drugs shows that collagen peptides support the structural integrity of the intestinal wall, crucial for healthy digestion.
  • Cardiovascular health: Collagen peptides contain proline, an amino acid essential for maintaining healthy blood vessels and overall cardiovascular function.
  • Muscle and joint health: Collagen peptides are rich in glycine and arginine, which support the growth and development of healthy muscles and tissues, as well as maintaining optimal bone mineral density.

Integrating collagen and vitamin C into your routine

The study's findings provide a strong scientific basis for incorporating collagen and vitamin C into daily health routines. Whether you're looking to maintain youthful skin, improve hair quality, or support overall health, this powerful combination offers a non-invasive and effective solution. With the backing of clinical evidence, it's time to consider these supplements as part of a comprehensive wellness strategy. Start today and experience the transformative benefits for yourself. Sources for this article include: MindBodyGreen.com Wiley.com PubMed.com MDhair.co
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